6 edition of Calculation method for compressible three dimensional turbulent boundary layer flows found in the catalog.
Bibliographical references: p.35-37.
|Statement||von Karman Institute for Fluid Dynamics|
|Publishers||von Karman Institute for Fluid Dynamics|
|The Physical Object|
|Pagination||xvi, 114 p. :|
|Number of Pages||88|
|2||von Karman Institute for Fluid Dynamics. Technical note -- 167|
- File Size: 10MB.
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It is unnecessary to calculatiom TDM for the majority of medications, and it is used mainly for monitoring drugs with narrow therapeutic ranges, drugs with marked pharmacokinetic variability, medications for which target concentrations are difficult to monitor, and drugs known to cause therapeutic and adverse effects. The process of TDM is predicated on boindary assumption that there is a definable relationship between dose and plasma or blood drug concentration, and between concentration and therapeutic effects.
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